How Do Modulators Affect the Orthosteric and Allosteric Binding Pockets?-Reference-Cited by-同舟云学术

How Do Modulators Affect the Orthosteric and Allosteric Binding Pockets?

Published:2022-03-17 Issue:7 Volume:13 Page:959-977
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Chen Chih-Jung¹²,Jiang Chen¹²,Yuan Jiayi¹²,Chen Maozi¹²,Cuyler Jacob¹²,Xie Xiang-Qun¹²³⁴^ORCID,Feng Zhiwei¹²^ORCID

Affiliation:

1. Department of Pharmaceutical Sciences and Computational Chemical Genomics Screening Center, School of Pharmacy, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, United States

2. National Center of Excellence for Computational Drug Abuse Research, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, United States

3. Drug Discovery Institute, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, United States

4. Departments of Computational Biology and Structural Biology, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, United States

Funder

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.1c00749

Reference120 articles.

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2. Computational Advances for the Development of Allosteric Modulators and Bitopic Ligands in G Protein-Coupled Receptors

3. Investigating the molecular mechanism of positive and negative allosteric modulators in the calcium-sensing receptor dimer

4. Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts

5. From ATP to AZD6140: The discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis

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