Optimizing Epitope Conformational Ensembles Using α-Synuclein Cyclic Peptide “Glycindel” Scaffolds: A Customized Immunogen Method for Generating Oligomer-Selective Antibodies for Parkinson’s Disease-Reference-Cited by-同舟云学术

Optimizing Epitope Conformational Ensembles Using α-Synuclein Cyclic Peptide “Glycindel” Scaffolds: A Customized Immunogen Method for Generating Oligomer-Selective Antibodies for Parkinson’s Disease

Published:2022-07-15 Issue:15 Volume:13 Page:2261-2280
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Hsueh Shawn C. C.¹^ORCID,Aina Adekunle¹^ORCID,Roman Andrei Yu.²,Cashman Neil R.²,Peng Xubiao¹^ORCID,Plotkin Steven S.¹³^ORCID

Affiliation:

1. Department of Physics and Astronomy, The University of British Columbia, Vancouver, BC V6T 1Z1, Canada

2. Djavad Mowafaghian Centre for Brain Health, The University of British Columbia, Vancouver, BC V6T 2B5, Canada

3. Genome Science and Technology Program, The University of British Columbia, Vancouver, BC V6T 1Z1, Canada

Funder

Canadian Institutes of Health Research

Compute Canada

Alberta Innovates

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.1c00567

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