Structural Features of Iperoxo–BQCA Muscarinic Acetylcholine Receptor Hybrid Ligands Determining Subtype Selectivity and Efficacy
Author:
Affiliation:
1. Medicinal Chemistry, Monash University, 381 Royal Parade, Parkville, Victoria 3052, Australia
2. Drug Discovery Biology, Monash Institute of Pharmaceutical Sciences, Monash University, 381 Royal Parade, Parkville, Victoria 3052, Australia
Funder
National Health and Medical Research Council
Australian Research Council
Publisher
American Chemical Society (ACS)
Subject
Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.1c00572
Reference42 articles.
1. Decreased cortical muscarinic receptors define a subgroup of subjects with schizophrenia
2. Possible Involvement of Muscarinic Receptors in Psychiatric Disorders: A Focus on Schizophrenia and Mood Disorders
3. Antichounergic Psychotomimetic Agents
4. Physostigmine and Arecoline: Effects of Intravenous Infusions in Alzheimer Presenile Dementia
5. Effects of Xanomeline, a Selective Muscarinic Receptor Agonist, on Cognitive Function and Behavioral Symptoms in Alzheimer Disease
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