Scaffold Hybridization Strategy Leads to the Discovery of Dopamine D3 Receptor-Selective or Multitarget Bitopic Ligands Potentially Useful for Central Nervous System Disorders

Author:

Bonifazi Alessandro12ORCID,Newman Amy H.1ORCID,Keck Thomas M.13ORCID,Gervasoni Silvia4,Vistoli Giulio4ORCID,Del Bello Fabio2ORCID,Giorgioni Gianfabio2ORCID,Pavletić Pegi2,Quaglia Wilma2ORCID,Piergentili Alessandro2ORCID

Affiliation:

1. Medicinal Chemistry Section, Molecular Targets and Medications Discovery Branch, National Institute on Drug Abuse—Intramural Research Program, National Institutes of Health, 333 Cassell Drive, Baltimore, Maryland 21224, United States

2. School of Pharmacy, Medicinal Chemistry Unit, University of Camerino, Via S. Agostino 1, Camerino 62032, Italy

3. Department of Chemistry & Biochemistry, Department of Molecular & Cellular Biosciences, Rowan University, 201 Mullica Hill Rd, Glassboro, New Jersey 08028, United States

4. Department of Pharmaceutical Sciences, University of Milan, Via Mangiagalli 25, Milano 20133, Italy

Funder

National Institute of Development Administration

Universit?? degli Studi di Camerino

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

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