Understanding the Polypharmacological Profiles of Triple Reuptake Inhibitors by Molecular Simulation-Reference-Cited by-同舟云学术

Understanding the Polypharmacological Profiles of Triple Reuptake Inhibitors by Molecular Simulation

Published:2021-05-12 Issue:11 Volume:12 Page:2013-2026
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Tu Gao¹,Fu Tingting¹²,Yang Fengyuan¹²,Yang Jingyi¹,Zhang Zhao¹,Yao Xiaojun³^ORCID,Xue Weiwei¹⁴^ORCID,Zhu Feng¹²^ORCID

Affiliation:

1. School of Pharmaceutical Sciences, Chongqing Key Laboratory of Natural Product Synthesis and Drug Research, Chongqing University, Chongqing 401331, China

2. College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China

3. State Key Laboratory of Applied Organic Chemistry and Department of Chemistry, Lanzhou University, Lanzhou 730000, China

4. Central Nervous System Drug Key Laboratory of Sichuan Province, Luzhou 646106, China

Funder

Ministry of Education of the People's Republic of China

National Natural Science Foundation of China

Technology Innovation and Application Demonstration Project of Chongqing

Central Nervous System Drug Key Laboratory of Sichuan Province

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.1c00127

Reference70 articles.

1. Multitarget Drug Discovery and Polypharmacology

2. A perspective on multi‐target drug discovery and design for complex diseases

3. Multi-target pharmacology: possibilities and limitations of the “skeleton key approach” from a medicinal chemist perspective

4. The Multi-Target Drug Design Era is Here, Consider it

5. Computational polypharmacology: a new paradigm for drug discovery

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