Development of Thiochroman Dioxide Analogues of Benzothiadiazine Dioxides as New Positive Allosteric Modulators of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors

Author:

Etsè Koffi Sénam1,Dorosz Jerzy2,McLain Christensen Katrine2,Thomas Jean-Yves3,Botez Pop Iuliana3,Goffin Eric1,Colson Thomas1,Lestage Pierre3,Danober Laurence3,Pirotte Bernard1,Kastrup Jette Sandholm42ORCID,Francotte Pierre1ORCID

Affiliation:

1. Center for Interdisciplinary Research on Medicines (CIRM) − Laboratory of Medicinal Chemistry, University of Liège, Avenue Hippocrate 15 (B36), B-4000 Liège, Belgium

2. Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark

3. Institut de Recherches Servier, 125 Chemin de Ronde, F-78290 Croissy-sur-Seine, France

4. Research Cluster on Molecular Neuroprotection, University of Copenhagen, DK-2100 Copenhagen, Denmark

Funder

Det Frie Forskningsråd

Fonds Léon Fredericq

DanScatt

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

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