Metabolite Study and Structural Authentication for the First-in-Human Use Sphingosine-1-phosphate Receptor 1 Radiotracer-Reference-Cited by-同舟云学术

Metabolite Study and Structural Authentication for the First-in-Human Use Sphingosine-1-phosphate Receptor 1 Radiotracer

Published:2024-04-18 Issue:9 Volume:15 Page:1882-1892
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Qiu Lin¹^ORCID,Jiang Hao¹,Cho Kevin²^ORCID,Yu Yanbo¹,Jones Lynne A.¹,Huang Tianyu¹^ORCID,Perlmutter Joel S.¹³,Gropler Robert J.¹,Brier Matthew R.³,Patti Gary J.²^ORCID,Benzinger Tammie L. S.¹,Tu Zhude¹^ORCID

Affiliation:

1. Department of Radiology, Washington University School of Medicine, Saint Louis, Missouri 63110, United States

2. Center for Mass Spectrometry and Metabolic Tracing, Department of Chemistry, Department of Medicine, Washington University, Saint Louis, Missouri 63130, United States

3. Departments of Neurology, Neuroscience, Physical Therapy and Occupational Therapy, Washington University School of Medicine, Saint Louis, Missouri 63110, United States

Funder

U.S. Department of Health and Human Services

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.4c00077

Reference39 articles.

1. Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential

2. The alliance of sphingosine-1-phosphate and its receptors in immunity

3. The Immune Modulator FTY720 Targets Sphingosine 1-Phosphate Receptors

4. Sphingosine-1-phosphate receptor-1 (S1P1) is expressed by lymphocytes, dendritic cells, and endothelium and modulated during inflammatory bowel disease

5. FTY720, a Synthetic Sphingosine 1 Phosphate Analogue, Inhibits Development of Atherosclerosis in Low-Density Lipoprotein Receptor–Deficient Mice

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