4-Amidophenol Quinone Methide Precursors: Effective and Broad-Scope Nonoxime Reactivators of Organophosphorus-Inhibited Cholinesterases and Resurrectors of Organophosphorus-Aged Acetylcholinesterase-Reference-Cited by-同舟云学术

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4-Amidophenol Quinone Methide Precursors: Effective and Broad-Scope Nonoxime Reactivators of Organophosphorus-Inhibited Cholinesterases and Resurrectors of Organophosphorus-Aged Acetylcholinesterase

Published:2024-04-15 Issue:9 Volume:15 Page:1813-1827
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Lovins Alex R.¹^ORCID,Miller Kevin A.¹^ORCID,Buck Anne K.¹,Ensey D. Sophia¹,Homoelle Rose K.¹,Murtha Megan C.¹,Ward Nathan A.¹,Shanahan Liam A.¹,Gutti Gopichand²,Shriwas Pratik²,McElroy Craig A.²^ORCID,Callam Christopher S.¹^ORCID,Hadad Christopher M.¹^ORCID

Affiliation:

1. Department of Chemistry and Biochemistry, College of Arts and Sciences, Ohio State University, Columbus, Ohio 43210, United States

2. Department of Medicinal Chemistry and Pharmacognosy, College of Pharmacy, Ohio State University, Columbus, Ohio 43210, United States

Funder

Defense Threat Reduction Agency

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.4c00011

Reference36 articles.

1. Acetylcholine and Nerve Activity

2. Acetylcholinesterase Inhibitors: Pharmacology and Toxicology

3. A Novel Fluorine-18 β-Fluoroethoxy Organophosphate Positron Emission Tomography Imaging Tracer Targeted to Central Nervous System Acetylcholinesterase

4. Respiratory Complications of Organophosphorus Nerve Agent and Insecticide Poisoning. Implications for Respiratory and Critical Care

5. THE REVERSAL BY OXIMES OF NEUROMUSCULAR BLOCK PRODUCED BY ANTICHOLINESTERASES

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