AE Succinimide, an Analogue of Methyllycaconitine, When Bound Generates a Nonconducting Conformation of the α4β2 Nicotinic Acetylcholine Receptor
Author:
Affiliation:
1. Brain and Mind Centre, School of Pharmacy, Faculty of Medicine and Health, Sydney, NSW 2050, The University of Sydney
2. Research School of Chemistry, College of Science, The Australian National University, Canberra, ACT 2601, Australia
Funder
University of Sydney
National Health and Medical Research Council
Australian Research Council
Publisher
American Chemical Society (ACS)
Subject
Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.9b00525
Reference30 articles.
1. The wonderland of neuronal nicotinic acetylcholine receptors
2. Understanding structure-function relationships of the human neuronal acetylcholine receptor: insights from the first crystal structures of neuronal subunits
3. Emerging structure of the Nicotinic Acetylcholine receptors
4. Neuronal nicotinic receptors: from structure to pathology
5. Molecular mechanisms and binding site locations for noncompetitive antagonists of nicotinic acetylcholine receptors
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