The Brain Exposure Efficiency (BEE) Score-Reference-Cited by-同舟云学术

登录注册会员服务联系我们

The Brain Exposure Efficiency (BEE) Score

Published:2019-12-09 Issue:2 Volume:11 Page:205-224
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Gupta Mayuri¹^ORCID,Bogdanowicz Thomas¹,Reed Mark A.¹,Barden Christopher J.¹,Weaver Donald F.¹²³⁴^ORCID

Affiliation:

1. Krembil Research Institute, University Health Network, 60 Leonard Avenue, Toronto, Ontario M5T 2S8, Canada

2. Department of Medicine, University of Toronto, Toronto, Ontario M5G 2C4, Canada

3. Department of Chemistry, University of Toronto, Toronto, Ontario M5S 3H6, Canada

4. Department of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario M5S 3M2 Canada

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.9b00650

Reference140 articles.

1. Development, maintenance and disruption of the blood-brain barrier

2. Structure and function of the blood–brain barrier

3. Modelling of the blood–brain barrier in drug discovery and development

4. Neurovascular regulation in the normal brain and in Alzheimer's disease

5. Log(BB), PS products and in silico models of drug brain penetration

Cited by 13 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Experimental and Computational Methods to Assess Central Nervous System Penetration of Small Molecules;Molecules;2024-03-13

2. Designing drugs optimized for both blood–brain barrier permeation and intra-cerebral partition;Expert Opinion on Drug Discovery;2023-12-25

3. Using the LeiCNS-PK3.0 Physiologically-Based Pharmacokinetic Model to Predict Brain Extracellular Fluid Pharmacokinetics in Mice;Pharmaceutical Research;2023-07-13

4. The PBPK LeiCNS-PK3.0 framework predicts Nirmatrelvir (but not Remdesivir or Molnupiravir) to achieve effective concentrations against SARS-CoV-2 in human brain cells;European Journal of Pharmaceutical Sciences;2023-02

5. A privileged dual action Alzheimer's disease therapeutic platform targeting immunopathic and proteopathic mechanisms: (E)-3-styrylindoles as inhibitors of indoleamine 2,3-dioxygenase-mediated tryptophan metabolism and β-amyloid aggregation;Canadian Journal of Chemistry;2022-09-01

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号京ICP备18003416号-3