Pharmacological Characterizations of anti-Dementia Memantine Nitrate via Neuroprotection and Vasodilation in Vitro and in Vivo

Author:

Mak Shinghung12,Liu Zheng345,Wu Liangmiao3,Guo Baojian13,Luo Fangcheng35,Liu Ziyan3,Hu Shengquan12,Wang Jiajun2,Cui Guozhen6,Sun Yewei3,Wang Yuqiang3,Zhang Gaoxiao3,Han Yifan12ORCID,Zhang Zaijun37

Affiliation:

1. State Key Laboratory of Chinese Medicine and Molecular Pharmacology (Incubation), The Hong Kong Polytechnic University Shenzhen Research Institute, Shenzhen 518057, China

2. Department of Applied Biology and Chemical Technology, Institute of Modern Chinese Medicine, The Hong Kong Polytechnic University, Hung Hom, Hong Kong, China

3. Institute of New Drug Research and Guangzhou Key Laboratory of Innovative Chemical Drug Research in Cardio-cerebrovascular Diseases, Jinan University College of Pharmacy, Guangzhou 510632, China

4. Foshan Stomatology Hospital, School of Stomatology and Medicine, Foshan University, Foshan 528000, China

5. Foshan Magpie Pharmaceuticals Co., Ltd., Foshan, 528000 Guangdong, China

6. Department of Bioengineering, Zunyi Medical University Zhuhai Campus, Zhuhai 519041, China

7. International Cooperative Laboratory of Traditional Chinese Medicine Modernization and Innovative Drug Development of Chinese Ministry of Education (MOE), Jinan University College of Pharmacy, 601 Huangpu Avenue West, Guangzhou 510632, China

Funder

Research Grants Council, University Grants Committee

Ministry of Science and Technology of the People's Republic of China

Innovation and Technology Fund

National Natural Science Foundation of China

Hong Kong Polytechnic University

Hong Kong Special Administrative Region of the People's Republic of China

Shenzhen Basic Research Program

Guangdong Province

Scientific Projects of Guangzhou

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

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