Cryptic Sites in Tau Fibrils Explain the Preferential Binding of the AV-1451 PET Tracer toward Alzheimer’s Tauopathy-Reference-Cited by-同舟云学术

Cryptic Sites in Tau Fibrils Explain the Preferential Binding of the AV-1451 PET Tracer toward Alzheimer’s Tauopathy

Published:2021-06-21 Issue:13 Volume:12 Page:2437-2447
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Murugan N. Arul¹^ORCID,Nordberg Agneta²³,Ågren Hans⁴⁵^ORCID

Affiliation:

1. School of Engineering Sciences in Chemistry, Biotechnology and Health, KTH Royal Institute of Technology, S-106 91 Stockholm, Sweden

2. Division of Clinical Geriatrics, Center for Alzheimer Research, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, S-141 86 Stockholm, Sweden

3. Theme Aging, The Aging Brain, Karolinska University Hospital, Huddinge, S-141 86 Stockholm, Sweden

4. Department of Physics and Astronomy, Uppsala University, Uppsala SE-75120, Sweden

5. College of Chemistry and Chemical Engineering, Henan University, Kaifeng, Henan 475004, P. R. China

Funder

Stiftelsen f??r??Strategisk Forskning

Swedish National Infrastructure for Computing

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.0c00340

Reference50 articles.

1. Unfolding the role of protein misfolding in neurodegenerative diseases

2. Toxic Proteins in Neurodegenerative Disease

3. Neurodegenerative Tauopathies

4. Tauopathies

5. Biochemistry and molecular biology of tauopathies

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