Design, Synthesis, and Functional Evaluation of a Novel Series of Phosphonate-Functionalized 1,2,3-Triazoles as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors-Reference-Cited by-同舟云学术

Design, Synthesis, and Functional Evaluation of a Novel Series of Phosphonate-Functionalized 1,2,3-Triazoles as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors

Published:2020-07-28 Issue:17 Volume:11 Page:2688-2704
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Nielsen Beatriz Elizabeth¹^ORCID,Stabile Santiago²^ORCID,Vitale Cristian²^ORCID,Bouzat Cecilia¹^ORCID

Affiliation:

1. Departamento de Biologı́a, Bioquı́mica y Farmacia, Instituto de Investigaciones Bioquı́micas de Bahı́a Blanca (INIBIBB), Departamento de Biologı́a, Bioquı́mica y Farmacia, Universidad Nacional del Sur-Consejo Nacional de Investigaciones Cientı́ficas y Técnicas (CONICET), Bahía Blanca 8000, Buenos Aires, Argentina

2. Instituto de Quı́mica del Sur (INQUISUR), Departamento de Quı́mica, Universidad Nacional del Sur-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Bahía Blanca 8000, Buenos Aires, Argentina

Funder

Universidad Nacional del Sur

Fondo para la Investigaci?n Cient?fica y Tecnol?gica

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.0c00348

Reference52 articles.

1. α7 Nicotinic acetylcholine receptors and their role in cognition

2. The therapeutic promise of positive allosteric modulation of nicotinic receptors