1. Multiple Sclerosis Group, Neuroscience Area, Biodonostia Research Institute, San Sebastian 20014, Spain
2. Center for Cooperative Research in Biomaterials (CIC biomaGUNE), Basque Research and Technology Alliance (BRTA), Paseo Miramón 182, Donostia, San Sebastián 20014, Spain
3. Spanish Network of Multiple Sclerosis (REEM),, Barcelona 08028Spain
4. Neurology Department, Donostia University Hospital, Osakidetza, San Sebastián 20014, Spain
5. Ikerbasque, Basque Foundation for Science, Bilbao 48009, Spain