Altered Hinge Conformations in APP Transmembrane Helix Mutants May Affect Enzyme–Substrate Interactions of γ-Secretase-Reference-Cited by-同舟云学术

Altered Hinge Conformations in APP Transmembrane Helix Mutants May Affect Enzyme–Substrate Interactions of γ-Secretase

Author:

Silber Mara¹,Hitzenberger Manuel²,Zacharias Martin²,Muhle-Goll Claudia¹³^ORCID

Affiliation:

1. Institute for Biological Interfaces 4, Karlsruhe Institute of Technology, P.O. Box 3640, 76021 Karlsruhe, Germany

2. Physics Department T38, Technical University of Munich, James-Frank-Str. 1, 85748 Garching, Germany

3. Institute of Organic Chemistry, Karlsruhe Institute of Technology, Fritz-Haber-Weg 6, 76131 Karlsruhe, Germany

Funder

Carl-Zeiss-Stiftung

Helmholtz-Gemeinschaft

Deutsche Forschungsgemeinschaft

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

Reference59 articles.

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