From Methaqualone and Beyond: Structure–Activity Relationship of 6-, 7-, and 8-Substituted 2,3-Diphenyl-quinazolin-4(3H)-ones and in Silico Prediction of Putative Binding Modes of Quinazolin-4(3H)-ones as Positive Allosteric Modulators of GABAA Receptors-Reference-Cited by-同舟云学术

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From Methaqualone and Beyond: Structure–Activity Relationship of 6-, 7-, and 8-Substituted 2,3-Diphenyl-quinazolin-4(3H)-ones and in Silico Prediction of Putative Binding Modes of Quinazolin-4(3H)-ones as Positive Allosteric Modulators of GABAA Receptors

Published:2020-11-10 Issue:24 Volume:11 Page:4362-4375
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Wang Peng-Fei¹²,Jensen Anders A.¹,Bunch Lennart¹^ORCID

Affiliation:

1. Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen 2100, Denmark

2. School of Pharmaceutical Sciences and Innovative Drug Research Centre, Chongqing University, Chongqing 400044, P.R. China

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.0c00600

Reference39 articles.

1. International Union of Pharmacology. LXX. Subtypes of γ-Aminobutyric AcidAReceptors: Classification on the Basis of Subunit Composition, Pharmacology, and Function. Update

2. GABA A Receptors and the Diversity in their Structure and Pharmacology

3. Crystal structure of a human GABAA receptor

4. Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer

5. GABA-A receptor subtypes in the brain: a paradigm for CNS drug discovery?

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1. Structural insights into GABAA receptor potentiation by Quaalude;Nature Communications;2024-06-19

2. Synthesis, In Vivo Anticonvulsant Activity Evaluation and In Silico Studies of Some Quinazolin-4(3H)-One Derivatives;Molecules;2024-04-24

3. Synthesis and Biological Evaluation of 2-Substituted Quinazolin-4(3H)-Ones with Antiproliferative Activities;Molecules;2023-12-02

4. Review of the experiences of users of methaqualone and methaqualone derivatives. An analysis of online forums;Archives of Forensic Medicine and Criminology;2023-08-28

5. Synthesis of Quinazolin-4(3H)-ones via a novel approach;Journal of Saudi Chemical Society;2023-03

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