Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate Receptors-Reference-Cited by-同舟云学术

Distinct GluN1 and GluN2 Structural Determinants for Subunit-Selective Positive Allosteric Modulation of N-Methyl-d-aspartate Receptors

Published:2020-12-16 Issue:1 Volume:12 Page:79-98
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Strong Katie L.¹²,Epplin Matthew P.²,Ogden Kevin K.¹,Burger Pieter B.²,Kaiser Thomas M.²,Wilding Timothy J.³,Kusumoto Hiro¹,Camp Chad R.¹^ORCID,Shaulsky Gil¹,Bhattacharya Subhrajit⁴,Perszyk Riley E.¹,Menaldino David S.²,McDaniel Miranda J.¹,Zhang Jing¹,Le Phuong¹,Banke Tue G.¹,Hansen Kasper B.¹⁵^ORCID,Huettner James E.³,Liotta Dennis C.²^ORCID,Traynelis Stephen F.¹^ORCID

Affiliation:

1. Department of Pharmacology, Emory University, 1510 Clifton Road, Atlanta, Georgia 30322, United States

2. Department of Chemistry, Emory University, 1515 Dickey Drive, Atlanta, Georgia 30322, United States

3. Department of Cell Biology and Physiology, Washington University, St Louis, Missouri 63110, United States

4. Department of Drug Discovery and Development, Auburn University, Auburn, Alabama 36849, United States

5. Center for Biomolecular Structure and Dynamics, Center for Structural and Functional Neuroscience, Division for Biological Sciences, University of Montana, 32 Campus Drive, Missoula, Montana 59812, United States

Funder

U.S. Department of Health and Human Services

Johnson and Johnson

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.0c00561

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1. Glutamate Receptor Ion Channels: Structure, Regulation, and Function

2. NMDA-receptor activation increases cytoplasmic calcium concentration in cultured spinal cord neurones