Effect of Bulky <i>N</i>-Dibenzofuranylmethyl Substitution on the 5-HT<sub>2</sub> Receptor Affinity and Efficacy of a Psychedelic Phenethylamine-Reference-Cited by-同舟云学术

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Effect of Bulky N-Dibenzofuranylmethyl Substitution on the 5-HT₂ Receptor Affinity and Efficacy of a Psychedelic Phenethylamine

Published:2024-01-19 Issue:3 Volume:15 Page:608-616
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Soares Breno A.¹²,Yempala Thirumal¹,Martínez-Afani Darío¹,Acevedo-Fuentes Williams¹,Brea José³,Loza María Isabel³^ORCID,Cimadevila Marta³,Cassels Bruce K.¹^ORCID

Affiliation:

1. Department of Chemistry, Faculty of Sciences, University of Chile, Santiago 780003, Chile

2. Institute of Exact and Technological Sciences, Federal University of Jataí, Jataí 75804 Goiás, Brazil

3. Biofarma Research Group, CiMUS, Departamento de Farmacología, Facultad de Farmacia, Universidade de Santiago de Compostela, Santiago 15705, Spain

Funder

Agencia Estatal de Investigaci?n

Xunta de Galicia

Universidad de Chile

Fondo Nacional de Desarrollo Cient?fico y Tecnol?gico

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.3c00639

Reference53 articles.

1. 5-Hydroxytryptamine 2A receptor antagonists as potential treatment for psychiatric disorders

2. Molecular and Cellular Basis of Hallucinogen Action

3. Therapeutic use of serotoninergic hallucinogens: A review of the evidence and of the biological and psychological mechanisms

4. Effects of 5-HT2C receptor stimulation in male mice on behaviour and Fos expression: Feeding, reward and impulsivity

5. Targeting the 5-HT2C Receptor in Biological Context and the Current State of 5-HT2C Receptor Ligand Development

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