Characterization of (R)- and (S)-[18F]OF-NB1 in Rodents as Positron Emission Tomography Probes for Imaging GluN2B Subunit-Containing N-Methyl-<scp>d</scp>-Aspartate Receptors-Reference-Cited by-同舟云学术

Characterization of (R)- and (S)-[¹⁸F]OF-NB1 in Rodents as Positron Emission Tomography Probes for Imaging GluN2B Subunit-Containing N-Methyl-d-Aspartate Receptors

Published:2023-12-07 Issue:24 Volume:14 Page:4323-4334
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Ahmed Hazem¹^ORCID,Wallimann Rahel¹,Gisler Livio¹,Elghazawy Nehal H.²,Gruber Stefan¹^ORCID,Keller Claudia¹,Liang Steven H.³^ORCID,Sippl Wolfgang²^ORCID,Haider Ahmed³⁴^ORCID,Ametamey Simon M.¹^ORCID

Affiliation:

1. Institute of Pharmaceutical Sciences, ETH Zurich, Vladimir-Prelog-Weg 4, 8093 Zurich, Switzerland

2. Institute of Pharmacy, Department of Medicinal Chemistry, Martin-Luther-University Halle-Wittenberg, W.-Langenbeck-Str. 4, 06120 Halle, Germany

3. Division of Nuclear Medicine and Molecular Imaging, Massachusetts General Hospital & Department of Radiology, Harvard Medical School, Boston, Massachusetts 02114, United States

4. Department of Nuclear Medicine, University Hospital Zurich, Rämistrasse 100, 8091 Zurich, Switzerland

Funder

Schweizerischer Nationalfonds zur F?rderung der Wissenschaftlichen Forschung

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.3c00519

Reference60 articles.

1. NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

2. NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders

3. Glutamate Receptor Ion Channels: Structure, Regulation, and Function

4. Structure, function, and allosteric modulation of NMDA receptors

5. A structural biology perspective on NMDA receptor pharmacology and function