1. Department of Biochemistry, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil
2. Department of Chemistry, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil
3. Graduate Program in Health Sciences, Federal University of Health Sciences of Porto Alegre, Porto Alegre 90050-170, RS, Brazil
4. Department of Pharmacology, Federal University of Santa Catarina, Florianópolis 88040-900, SC, Brazil
5. Department of Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461, United States