Reformulating a Pharmacophore for 5-HT2A Serotonin Receptor Antagonists
Author:
Affiliation:
1. Department of Physiology and Biophysics, School of Medicine, and ‡Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, Virginia 23298, United States
Funder
National Heart, Lung, and Blood Institute
National Institute of Mental Health
Publisher
American Chemical Society (ACS)
Subject
Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.6b00162
Reference21 articles.
1. Development of a Receptor-Interaction Model for Serotonin 5-HT2 Receptor Antagonists. Predicting Selectivity with Respect to Dopamine D2 Receptors
2. Construction of a Detailed Serotoninergic 5-HT2a Receptor Model
3. Structure-Activity Relationship Studies of CNS Agents, Part 25: 4,6-Di(heteroaryl)-2-(N-methylpiperazino)pyrimidines as New, Potent 5-HT2A Receptor Ligands: A Verification of the Topographic Model
4. Application of Ligand SAR, Receptor Modeling and Receptor Mutagenesis to the Discovery and Development of a New class of 5-HT2A Ligands
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