Increase of Positive Net Charge and Conformational Rigidity Enhances the Efficacy of d-Enantiomeric Peptides Designed to Eliminate Cytotoxic Aβ Species-Reference-Cited by-同舟云学术

Increase of Positive Net Charge and Conformational Rigidity Enhances the Efficacy of d-Enantiomeric Peptides Designed to Eliminate Cytotoxic Aβ Species

Published:2016-06-09 Issue:8 Volume:7 Page:1088-1096
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Ziehm Tamar¹,Brener Oleksandr¹²,van Groen Thomas³,Kadish Inga³,Frenzel Daniel¹,Tusche Markus¹,Kutzsche Janine¹,Reiß Kerstin¹,Gremer Lothar¹²,Nagel-Steger Luitgard¹²,Willbold Dieter¹²

Affiliation:

1. Institute of Complex Systems, Structural Biochemistry (ICS-6), Forschungszentrum Jülich, 52425 Jülich, Germany

2. Institut für Physikalische Biologie, Heinrich-Heine-Universität Düsseldorf, 40225 Düsseldorf, Germany

3. Department of Cell, Developmental and Integrative Biology, University of Alabama at Birmingham (UAB), Birmingham, Alabama 35233, United States

Funder

Helmholtz Association

Forschungszentrum Jülich

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.6b00047

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