Dual Inhibition of PDK1 and Aurora Kinase A: An Effective Strategy to Induce Differentiation and Apoptosis of Human Glioblastoma Multiforme Stem Cells
Author:
Affiliation:
1. Scuola Normale Superiore, Piazza dei Cavalieri 7, I-56126 Pisa, Italy
2. Department of Pharmacy, University of Naples Federico II, Napoli, Italy
Funder
Università di Pisa
Ministero dell'Istruzione, dell'Università e della Ricerca
Publisher
American Chemical Society (ACS)
Subject
Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.6b00251
Reference70 articles.
1. Using the molecular classification of glioblastoma to inform personalized treatment
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4. Combined PDK1 and CHK1 inhibition is required to kill glioblastoma stem-like cells in vitro and in vivo
5. Small-Molecule Inhibitors of PDK1
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