Dipeptidyl Vinyl Sulfone as a Novel Chemical Tool to Inhibit HMGB1/NLRP3-Inflammasome and Inflamma-miRs in Aβ-Mediated Microglial Inflammation

Author:

Falcão Ana S.1,Carvalho Luís A. R.1,Lidónio Gonçalo1,Vaz Ana R.1,Lucas Susana D.1,Moreira Rui1,Brites Dora1

Affiliation:

1. Neuron Glia Biology in Health and Disease Group, Research Institute for Medicines (iMed.ULisboa), ‡Department of Biochemistry and Human Biology, §Medicinal Chemistry Group, Research Institute for Medicines (iMed.ULisboa), and ∥Department of Pharmaceutical Chemistry and Therapeutics, Faculty of Pharmacy, Universidade de Lisboa, Avenida Professor Gama Pinto, 1649-003 Lisbon, Portugal

Funder

European Commission

Fundação para a Ciência e a Tecnologia

Grupo de Estudo de Envelhecimento Cerebral e Demências

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

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