In Vivo Systems Response Profiling and Multivariate Classification of CNS Active Compounds: A Structured Tool for CNS Drug Discovery-Reference-Cited by-同舟云学术

In Vivo Systems Response Profiling and Multivariate Classification of CNS Active Compounds: A Structured Tool for CNS Drug Discovery

Published:2017-01-09 Issue:4 Volume:8 Page:785-797
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Waters Susanna¹²^ORCID,Svensson Peder²,Kullingsjö Johan²,Pontén Henrik¹,Andreasson Theresa³,Sunesson Ylva³,Ljung Elisabeth²,Sonesson Clas²,Waters Nicholas²

Affiliation:

1. Department of Pharmacology, Gothenburg University, SE-405 30 Gothenburg, Sweden

2. Integrative Research Laboratories Sweden AB, Gothenburg SE-413 46, Sweden

3. AstraZeneca R&D, SE-431 83 Mölndal, Sweden

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acschemneuro.6b00371

Reference69 articles.

1. Neoclassic Drug Discovery

2. The reductionist paradox: are the laws of chemistry and physics sufficient for the discovery of new drugs?

3. Target-based drug discovery: is something wrong?

4. How were new medicines discovered?

5. Why so Few Drug Targets: A Mathematical Explanation?

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