CoREST Complex-Selective Histone Deacetylase Inhibitors Show Prosynaptic Effects and an Improved Safety Profile To Enable Treatment of Synaptopathies-Reference-Cited by-同舟云学术

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CoREST Complex-Selective Histone Deacetylase Inhibitors Show Prosynaptic Effects and an Improved Safety Profile To Enable Treatment of Synaptopathies

Published:2018-11-29 Issue:3 Volume:10 Page:1729-1743
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Fuller Nathan O.¹^ORCID,Pirone Antonella¹,Lynch Berkley A.¹,Hewitt Michael C.¹,Quinton Maria S.¹,McKee Timothy D.¹,Ivarsson Magnus¹

Affiliation:

1. Rodin Therapeutics, 300 Technology Square, Cambridge, Massachusetts 02139, United States

Funder

Alzheimer's Drug Discovery Foundation

Michael J. Fox Foundation for Parkinson's Research

National Institute on Aging

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

http://pubs.acs.org/doi/pdf/10.1021/acschemneuro.8b00620

Reference54 articles.

1. Synaptic slaughter in Alzheimer's disease

2. Centrality of Early Synaptopathy in Parkinson’s Disease

3. Altered expression of synaptic proteins occurs early during progression of Alzheimer’s disease

4. Is synaptic loss a unique hallmark of Alzheimer's disease?

5. Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment

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1. Histone deacetylase complexes: Structure, regulation and function;Biochimica et Biophysica Acta (BBA) - Reviews on Cancer;2024-09

2. Class 1 histone deacetylases differentially modulate memory and synaptic genes in a spatial and temporal manner in aged and APP/PS1 mice;Brain Research;2024-08

3. Epigenetic Inhibitors as Alzheimer’s Disease Therapeutic Agents;Chemical and Pharmaceutical Bulletin;2024-07-01

4. Targeting epigenetic mechanisms in amyloid-β–mediated Alzheimer’s pathophysiology: unveiling therapeutic potential;Neural Regeneration Research;2024-03-01

5. Astrocytic transcription factors REST, YY1, and putative microRNAs in Parkinson’s disease and advanced therapeutic strategies;Gene;2024-01

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