Structural Modeling of γ-Secretase Aβn Complex Formation and Substrate Processing
Author:
Affiliation:
1. Physics Department T38, Technical University of Munich, James-Frank-Str. 1, 85748 Garching, Germany
Funder
Deutsche Forschungsgemeinschaft
Publisher
American Chemical Society (ACS)
Subject
Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.8b00725
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5. Two transmembrane aspartates in presenilin-1 required for presenilin endoproteolysis and γ-secretase activity
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