Comment on “In Vivo [18F]GE-179 Brain Signal Does Not Show NMDA-Specific Modulation with Drug Challenges in Rodents and Nonhuman Primates”-Reference-Cited by-同舟云学术

Comment on “In Vivo [18F]GE-179 Brain Signal Does Not Show NMDA-Specific Modulation with Drug Challenges in Rodents and Nonhuman Primates”

Published:2018-10-11 Issue:1 Volume:10 Page:768-772
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

McGinnity Colm J.¹²^ORCID,Årstad Erik³^ORCID,Beck Katherine⁴,Brooks David J.⁵⁶,Coles Jonathan P.⁷,Duncan John S.⁸⁹,Galovic Marian⁸⁹¹⁰,Hinz Rainer¹¹,Hirani Ella¹²,Howes Oliver D.⁴,Jones Paul A.¹²,Koepp Matthias J.⁸⁹,Luo Feng¹²,Riaño Barros Daniela A.¹³,Singh Nisha¹¹⁴,Trigg William¹²,Hammers Alexander¹²

Affiliation:

1. School of Biomedical Engineering and Imaging Sciences, King’s College London, London SE1 7EH, United Kingdom

2. King’s College London & Guy’s and St Thomas’ PET Centre, St Thomas’ Hospital, London SE1 7EH, United Kingdom

3. Institute of Nuclear Medicine and Department of Chemistry, University College London, London NW1 2BU, United Kingdom

4. Department of Psychosis Studies, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London SE5 8AF, United Kingdom

5. Department of Nuclear Medicine, Aarhus University, Aarhus 8200, Denmark

6. Institute of Neuroscience, Newcastle University, Newcastle upon Tyne NE1 7RU, United Kingdom

7. Division of Anaesthesia, Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, United Kingdom

8. Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, London WC1N 3BG, United Kingdom

9. Epilepsy Society, Gerrards Cross SL9 0RJ, United Kingdom

10. Department of Neurology, Kantonsspital St Gallen, 9007 St. Gallen, Switzerland

11. Wolfson Molecular Imaging Centre, University of Manchester, Manchester M20 3LJ, United Kingdom

12. GE Healthcare Ltd, Amersham HP7 9LL, United Kingdom

13. South London and Maudsley NHS Foundation Trust, Bethlem Royal Hospital, Beckenham, London BR3 3BX, United Kingdom

14. Department of Neuroimaging, Institute of Psychiatry, Psychology and Neuroscience, King’s College London, London SE5 8AF, United Kingdom

Funder

Research Councils UK

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.8b00246

Reference48 articles.

1. Imaging the PCP site of the NMDA ion channel

2. Synthesis and in vitro evaluation of 18F-labelled S-fluoroalkyl diarylguanidines: Novel high-affinity NMDA receptor antagonists for imaging with PET

3. Ex Vivo Tracing of NMDA and GABA-A Receptors in Rat Brain After Traumatic Brain Injury Using 18F-GE-179 and 18F-GE-194 Autoradiography

4. Initial Evaluation of 18F-GE-179, a Putative PET Tracer for Activated N-Methyl d-Aspartate Receptors

5. NMDA receptor binding in focal epilepsies

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