Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural Refinement and Evaluation of CNS Clearance-Reference-Cited by-同舟云学术

Advances in Sulfonamide Kappa Opioid Receptor Antagonists: Structural Refinement and Evaluation of CNS Clearance

Published:2022-04-12 Issue:8 Volume:13 Page:1315-1332
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Ma Huiyong¹²,Brust Tarsis³,Frankowski Kevin J.¹²^ORCID,Lovell Kimberly M.³,Cameron Michael D.⁴^ORCID,Bohn Laura M.³^ORCID,Aubé Jeffrey¹²^ORCID

Affiliation:

1. Center for Integrative Chemical Biology and Drug Discovery, UNC Eshelman School of Pharmacy, 125 Mason Farm Road, CB 7363, Chapel Hill, North Carolina 27599, United States

2. Department of Medicinal Chemistry, University of Kansas, 2034 Becker Drive, Lawrence, Kansas 66047, United States

3. Departments of Molecular Therapeutics and Neuroscience, The Scripps Research Institute, 130 Scripps Way, #2A2, Jupiter, Florida 33458, United States

4. Department of Molecular Therapeutics, The Scripps Research Institute, 130 Scripps Way, #2A1, Jupiter, Florida 33458, United States

Funder

National Institute on Drug Abuse

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/acschemneuro.2c00140

Reference23 articles.

1. kappa-Opioid receptor signaling and brain reward function

2. Dynorphin Is a Specific Endogenous Ligand of the κ Opioid Receptor

3. The Therapeutic Potential of Novel Kappa Opioid Receptor-based Treatments

4. Kappa opioid antagonists: Past successes and future prospects

5. Kappa-opioid ligands in the study and treatment of mood disorders

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