Pharmacological Mechanism of the Non-hallucinogenic 5-HT2A Agonist Ariadne and Analogs

Author:

Cunningham Michael J.1,Bock Hailey A.2,Serrano Inis C.1,Bechand Benjamin1,Vidyadhara D. J.3,Bonniwell Emma M.2,Lankri David1,Duggan Priscilla4ORCID,Nazarova Antonina L.5,Cao Andrew B.2,Calkins Maggie M.2,Khirsariya Prashant1ORCID,Hwu Christopher1,Katritch Vsevolod5ORCID,Chandra Sreeganga S.3,McCorvy John D.2,Sames Dalibor6ORCID

Affiliation:

1. Department of Chemistry, Columbia University, New York, New York 10027, United States

2. Department of Cell Biology, Neurobiology, and Anatomy, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, United States

3. Department of Neuroscience, Department of Neurology, Yale University, New Haven, Connecticut 06510, United States

4. Department of Neuroscience, Barnard College, New York, New York 10027, United States

5. Department of Quantitative and Computational Biology, Department of Chemistry, Dornsife Center for New Technologies in Drug Discovery and Development, Bridge Institute, Michelson Center for Convergent Biosciences, University of Southern California, Los Angeles, California 90089, United States

6. Department of Chemistry, and Zuckerman Institute of Mind, Brain, Behavior, Columbia University, New York, New York 10027, United States

Funder

Aligning Science Across Parkinson?s

Michael J. Fox Foundation for Parkinson's Research

National Institute of General Medical Sciences

Parkinson?s Foundation Research Center of Excellence

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

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