Design of a Coumarin-Based Fluorescent Probe for Efficient In Vivo Imaging of Amyloid-β Plaques

Author:

Cao Yangyang1,Liu Xiaohui23,Zhang Jingjing2,Liu Zhongmin1,Fu Yan2,Zhang Dong2,Zheng Mingyue23ORCID,Zhang Haiyan23ORCID,Xu Ming-Hua14ORCID

Affiliation:

1. Shenzhen Grubbs Institute and Department of Chemistry, Shenzhen Key Laboratory of Small Molecule Drug Discovery and Synthesis, Guangdong Provincial Key Laboratory of Catalysis, Southern University of Science and Technology, Shenzhen 518055, China

2. CAS Key Laboratory of Receptor Research, State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 201203, China

3. University of Chinese Academy of Sciences, Beijing 100049, China

4. School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang, Henan 453007, China

Funder

Ministry of Science and Technology of the People's Republic of China

Science, Technology and Innovation Commission of Shenzhen Municipality

Science and Technology Commission of Shanghai Municipality

National Natural Science Foundation of China

Key Laboratory of Receptor Structure and Function, Chinese Academy of Sciences

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

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