Stereodivergent Synthesis of 1,3-syn- and -anti-Tetrahydropyrimidinones
Author:
Affiliation:
1. University of Heidelberg, Department of Organic Chemistry, INF 270, D-69120 Heidelberg, Germany
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol101755m
Reference47 articles.
1. For examples of bioactive 1,3-amines of natural or synthetic origin, see:
2. Manzacidin D: An unprecedented secondary metabolite from the “living fossil” sponge Astrosclera willeyana
3. Enantioselective Synthesis of the Bromopyrrole Alkaloids Manzacidin A and C by Stereospecific C−H Bond Oxidation
4. 1,3-Diphenylpropane-1,3-diamines, VI: DNA-Interaction, Estrogen Receptor Affinity, and Cytostatic Activity of 1,3-Diphenylpropane-1,3-diamine-Pt(II) Complexes
5. Preparation, characterization, cytotoxicity, and mutagenicity of a pair of enantiomeric platinum(II) complexes with the potential to bind enantioselectively to DNA
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