1. Institute for Production Research and Development, The Nikka Whisky Distilling Co., Ltd., 967 Matsuyama, Masuo, Kashiwa, Chiba, 277-0033 Japan, Department of Preventive Dentistry, Tsurumi University School of Dental Medicine, 2-1-3 Tsurumi, Yokohama, 230-0063 Japan, and Department of Preventive Dentistry and Public Health, Tokyo Medical and Dental University, Faculty of Dentistry, 1-5-45 Yushima, Bunkyo-ku, Tokyo, 113-8549 Japan