Nanomolar Potency Pyrimido-pyrrolo-quinoxalinedione CFTR Inhibitor Reduces Cyst Size in a Polycystic Kidney Disease Model
Author:
Affiliation:
1. Departments of Medicine and Physiology, University of California, San Francisco, California 94143-0521
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm9009873
Reference30 articles.
1. Structure and Function of the CFTR Chloride Channel
2. The ABC protein turned chloride channel whose failure causes cystic fibrosis
3. Prevention of toxin-induced intestinal ion and fluid secretion by a small-molecule CFTR inhibitor
4. Lectin Conjugates as Potent, Nonabsorbable CFTR Inhibitors for Reducing Intestinal Fluid Secretion in Cholera
5. Electrolyte Transport in the Mammalian Colon: Mechanisms and Implications for Disease
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