(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic Acid, a Potent and Selective Agonist at the GluR5 Subtype of Ionotropic Glutamate Receptors. Synthesis, Modeling, and Molecular Pharmacology-Reference-Cited by-同舟云学术

(S)-2-Amino-3-(3-hydroxy-7,8-dihydro-6H-cyclohepta[d]isoxazol-4-yl)propionic Acid, a Potent and Selective Agonist at the GluR5 Subtype of Ionotropic Glutamate Receptors. Synthesis, Modeling, and Molecular Pharmacology

Published:2003-03-06 Issue:8 Volume:46 Page:1350-1358
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Brehm Lotte¹,Greenwood Jeremy R.¹,Hansen Kasper B.¹,Nielsen Birgitte¹,Egebjerg Jan¹,Stensbøl Tine B.¹,Bräuner-Osborne Hans¹,Sløk Frank A.¹,Kronborg Tine T. A.¹,Krogsgaard-Larsen Povl¹

Affiliation:

1. Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, 2 Universitetsparken, DK-2100 Copenhagen, Denmark, Department of Molecular Pharmacology, H. Lundbeck A/S, DK-2500 Valby, Denmark, and Department for Molecular and Structural Biology, University of Aarhus, DK-8000 Aarhus C, Denmark

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm0204441

Reference57 articles.

1. Glutamate in CNS disorders as a target for drug development: an update

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