Understanding the Structure−Activity Relationship of the Human Ether-a-go-go-Related Gene Cardiac K+ Channel. A Model for Bad Behavior
Author:
Affiliation:
1. Departments of Chemistry, Investigative PK, and Drug Safety Evaluation, Aventis Pharmaceuticals, Inc. Bridgewater, New Jersey 08807
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm0205651
Reference22 articles.
1. Torsades de pointes and proarrhythmia
2. A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel
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