Genetic Engineering, Expression, and Activity of a Chimeric Monoclonal Antibody−Avidin Fusion Protein for Receptor-Mediated Delivery of Biotinylated Drugs in Humans-Reference-Cited by-同舟云学术

Genetic Engineering, Expression, and Activity of a Chimeric Monoclonal Antibody−Avidin Fusion Protein for Receptor-Mediated Delivery of Biotinylated Drugs in Humans

Published:2008-02-16 Issue:3 Volume:19 Page:731-739
ISSN:1043-1802
Container-title:Bioconjugate Chemistry
language:en
Short-container-title:Bioconjugate Chem.

Author:

Boado Ruben J.¹,Zhang Yufeng¹,Zhang Yun¹,Xia Chun-fang¹,Wang Yuntao¹,Pardridge William M.¹

Affiliation:

1. ArmaGen Technologies, Inc., Santa Monica, California 90401, and Department of Medicine, University of California Los Angeles, Los Angeles, California 90024

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Pharmaceutical Science,Pharmacology,Biomedical Engineering,Bioengineering,Biotechnology

Link

https://pubs.acs.org/doi/pdf/10.1021/bc7004076

Reference19 articles.

1. Drug Targeting to the Brain

2. Humanization of anti-human insulin receptor antibody for drug targeting across the human blood–brain barrier

3. Genetic engineering, expression, and activity of a fusion protein of a human neurotrophin and a molecular Trojan horse for delivery across the human blood–brain barrier

4. Fusion Antibody for Alzheimer's Disease with Bidirectional Transport Across the Blood−Brain Barrier and Aβ Fibril Disaggregation

5. Genetic engineering of a lysosomal enzyme fusion protein for targeted delivery across the human blood-brain barrier

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