Identification and Characterization of Small Molecules as Potent and Specific EPAC2 Antagonists-Reference-Cited by-同舟云学术

Identification and Characterization of Small Molecules as Potent and Specific EPAC2 Antagonists

Published:2013-01-15 Issue:3 Volume:56 Page:952-962
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Chen Haijun¹²,Tsalkova Tamara¹²,Chepurny Oleg G.¹²,Mei Fang C.¹²,Holz George G.¹²,Cheng Xiaodong¹²,Zhou Jia¹²

Affiliation:

1. Department of Pharmacology and Toxicology and ‡Sealy Center for Structural Biology and Molecular Biophysics, University of Texas Medical Branch, Galveston, Texas 77555, United States

2. Department of Medicine and ∥Department of Pharmacology, State University of New York (SUNY), Upstate Medical University, Syracuse, New York 13210, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3014162

Reference34 articles.

1. The art of the chemical probe

2. Cyclic nucleotide research — still expanding after half a century

3. Epac is a Rap1 guanine-nucleotide-exchange factor directly activated by cyclic AMP

4. A Family of cAMP-Binding Proteins That Directly Activate Rap1

5. Epac: a new cAMP target and new avenues in cAMP research

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