4-Alkoxy-2-hydroxybenzaldehyde (AHB): A Versatile Aldehyde Linker for Solid-Phase Synthesis of C-Terminal Modified Peptides and Peptidomimetics
Author:
Affiliation:
1. Department of Chemistry, The University of Arizona, Tucson, Arizona 85721
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ol000048h
Reference4 articles.
1. Acid-labile handles for Fmoc solid-phase synthesis of peptide N-alkylamides
2. A reversible protecting group for the amide bond in peptides. Use in the synthesis of ‘difficult sequences’
3. Backbone Amide Linker (BAL) Strategy for Solid-Phase Synthesis of C-Terminal-Modified and Cyclic Peptides1,2,3
4. Structure-activity relationship of biphalin. The synthesis and biological activities of new analogues with modifications in positions 3 and 4
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1. Regioselective alkylation of 2,4-dihydroxybenzyaldehydes and 2,4-dihydroxyacetophenones;Tetrahedron Letters;2022-04
2. Facile construction of peptidomimetics by sequential C–S/C–N bond activation of Ugi-adducts;Organic Chemistry Frontiers;2021
3. Linkers for Solid-Phase Peptide Synthesis;Amino Acids, Peptides and Proteins in Organic Chemistry;2011-01-31
4. Development of a new microwave-assisted cleavable backbone amide linker (BAL): a comparative study;Org. Biomol. Chem.;2010
5. Backbone Amide Linker in Solid-Phase Synthesis;Chemical Reviews;2009-03-16
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