Discovery of Lacosamide Affinity Bait Agents That Exhibit Potent Voltage-Gated Sodium Channel Blocking Properties-Reference-Cited by-同舟云学术

Discovery of Lacosamide Affinity Bait Agents That Exhibit Potent Voltage-Gated Sodium Channel Blocking Properties

Published:2013-01-16 Issue:3 Volume:4 Page:463-474
ISSN:1948-7193
Container-title:ACS Chemical Neuroscience
language:en
Short-container-title:ACS Chem. Neurosci.

Author:

Park Ki Duk¹²,Yang Xiao-Fang¹²,Lee Hyosung¹²,Dustrude Erik T.¹²,Wang Yuying¹²,Khanna Rajesh¹²,Kohn Harold¹²

Affiliation:

1. Departments of Pharmacology and Toxicology, ‡Biochemistry and Molecular Biology, and §Program in Medical Neuroscience, Paul and Carole Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States

2. Division of Chemical Biology and Medicinal Chemistry, UNC Eshelman School of Pharmacy, and ⊥Department of Chemistry, University of North Carolina, Chapel Hill, North Carolina 27599, United States

Publisher

American Chemical Society (ACS)

Subject

Cell Biology,Cognitive Neuroscience,Physiology,Biochemistry,General Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/cn300188h

Reference52 articles.

1. Synthesis and Anticonvulsant Activities of N-Benzyl-2-acetamidopropionamide Derivatives

2. Lacosamide

3. Lacosamide, a novel anti-convulsant drug, shows efficacy with a wide safety margin in rodent models for epilepsy

4. Lacosamide: A Review of Preclinical Properties

5. The Investigational Anticonvulsant Lacosamide Selectively Enhances Slow Inactivation of Voltage-Gated Sodium Channels

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