The Sorbinil Trap: A Predicted Dead-End Complex Confirms the Mechanism of Aldose Reductase Inhibition
Author:
Affiliation:
1. The Harry B. and Aileen Gordon Diabetes Research Laboratory, Molecular Diabetes and Metabolism Section, Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030 and Signal Pharmaceuticals, San Diego, California 92121
Publisher
American Chemical Society (ACS)
Subject
Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/bi000789q
Reference32 articles.
1. Specific Binding of 4-Amino Folic Acid Analogues by Folic Acid Reductase
2. Aldose and Aldehyde Reductase Exhibit Isocorticosteroid Reductase Activity
3. Reduction of trioses by NADPH-dependent aldo-keto reductases. Aldose reductase, methylglyoxal, and diabetic complications.
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