1. Department of Organic Chemistry, Åbo Akademi University, Biskopsgatan 8, FIN-20500 Åbo, Finland, Biotie Therapies Corp., Viikinkaari 9, FIN-00710 Helsinki, Finland, Structural Chemistry Group, Department of Chemistry, University of Turku, Vatselankatu 2, FIN-20014 Turku, Finland, and Department of Chemistry, University of Jyväskylä, Survontie 9, FIN-40014 Jyväskylä, Finland