Macroamidine Formation in Bottromycins Is Catalyzed by a Divergent YcaO Enzyme-Reference-Cited by-同舟云学术

Macroamidine Formation in Bottromycins Is Catalyzed by a Divergent YcaO Enzyme

Published:2017-12-05 Issue:50 Volume:139 Page:18158-18161
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Franz Laura¹,Adam Sebastian¹,Santos-Aberturas Javier²,Truman Andrew W.²^ORCID,Koehnke Jesko¹^ORCID

Affiliation:

1. Workgroup Structural Biology of Biosynthetic Enzymes, Helmholtz Institute for Pharmaceutical Research Saarland, Helmholtz Centre for Infection Research, Saarland University, Campus Geb. E8.1, 66123 Saarbrücken, Germany

2. Department of Molecular Microbiology, John Innes Centre, Colney Lane, Norwich NR4 7UH, United Kingdom

Funder

Royal Society

Deutsche Forschungsgemeinschaft

Biotechnology and Biological Sciences Research Council

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/jacs.7b09898

Reference18 articles.

1. Mode of action of bottromycin A2. Release of aminoacyl- or peptidyl-tRNA from ribosomes.

2. Identification and characterisation of the gene cluster for the anti-MRSA antibiotic bottromycin: expanding the biosynthetic diversity of ribosomal peptides

3. Posttranslational β-methylation and macrolactamidination in the biosynthesis of the bottromycin complex of ribosomal peptide antibiotics

4. Structure and Biosynthesis of the Antibiotic Bottromycin D

5. Synthetic Biotechnology to Study and Engineer Ribosomal Bottromycin Biosynthesis

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