The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8
Author:
Affiliation:
1. Department of Chemistry and §Department of Molecular and Computational Biology, University of Southern California, Los Angeles, California 90089-0744, United States
Funder
Division of Chemistry
National Cancer Institute
Damon Runyon Cancer Research Foundation
Susan G. Komen for the Cure
American Cancer Society
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/jacs.7b02213
Reference53 articles.
1. The Emerging Significance of O-GlcNAc in Cellular Regulation
2. A little sugar goes a long way: The cell biology of O-GlcNAc
3. O-GlcNAc processing enzymes: catalytic mechanisms, substrate specificity, and enzyme regulation
4. The O-GlcNAc transferase gene resides on the X chromosome and is essential for embryonic stem cell viability and mouse ontogeny
5. Ogt -Dependent X-Chromosome-Linked Protein Glycosylation Is a Requisite Modification in Somatic Cell Function and Embryo Viability
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