Chemical Synthesis of Homogeneous Human Glycosyl-interferon-β That Exhibits Potent Antitumor Activity in Vivo-Reference-Cited by-同舟云学术

Chemical Synthesis of Homogeneous Human Glycosyl-interferon-β That Exhibits Potent Antitumor Activity in Vivo

Published:2012-03-15 Issue:12 Volume:134 Page:5428-5431
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Sakamoto Izumi¹,Tezuka Katsunari¹²,Fukae Kazuhiro¹,Ishii Kazuyuki¹,Taduru Keisuke¹,Maeda Masatoshi¹,Ouchi Masaki¹,Yoshida Kenta¹,Nambu Yuri³,Igarashi Jun³,Hayashi Naohiro³,Tsuji Takashi²⁴,Kajihara Yasuhiro⁵

Affiliation:

1. Glycotechnology Laboratory, Otsuka Chemical Co., Ltd., 134, Chudoji minami-machi, Shimogyo-ku, Kyoto 600-8815, Japan

2. Research Project for Glycoprotein Engineering funded by Otsuka Chemical Co., Ltd., Research Institute for Science and Technology, Tokyo University of Science, Noda, Chiba, 278-8510, Japan

3. Glycotechnology Laboratory, Otsuka Chemical Co., Ltd., 463, Kagasuno, Kawauchi, Tokushima, 771-0193, Japan

4. Department of Biological Science and Technology, Tokyo University of Science, Noda, Chiba, 278-8510, Japan

5. Department of Chemistry, Graduate School of Science, Osaka University, 1-1, Machikaneyama, Toyonaka, 560-0043, Japan

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja2109079

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1. The same but different

2. Post-translational modifications in the context of therapeutic proteins

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