Kinetic Studies of the Binding of Acridinecarboxamide Topoisomerase Poisons to DNA: Implications for Mode of Binding of Ligands with Uncharged Chromophores-Reference-Cited by-同舟云学术

Kinetic Studies of the Binding of Acridinecarboxamide Topoisomerase Poisons to DNA: Implications for Mode of Binding of Ligands with Uncharged Chromophores

Published:2002-01-17 Issue:4 Volume:45 Page:894-901
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Wakelin Laurence P. G.¹,Adams Adrienne¹,Denny William A.¹

Affiliation:

1. School of Medical Sciences, University of New South Wales, NSW 2052, Australia, Department of Biochemistry, University of Sydney, NSW 2006, Australia, and Auckland Cancer Society Research Centre, Faculty of Medicine and Health Science, University of Auckland, New Zealand

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm000473g

Reference32 articles.

1. DNA topoisomerase targeting drugs: mechanisms of action and perspectives

2. From amsacrine to DACA (N-[2-(dimethylamino)ethyl]acridine-4-carboxamide): Selectivity for topoisomerases I and II among acridine derivatives

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