Inhibition of Geranylgeranyl Diphosphate Synthase by Bisphosphonates: A Crystallographic and Computational Investigation-Reference-Cited by-同舟云学术

Inhibition of Geranylgeranyl Diphosphate Synthase by Bisphosphonates: A Crystallographic and Computational Investigation

Published:2008-08-23 Issue:18 Volume:51 Page:5594-5607
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Hudock Michael P.¹,Zhang Yonghui¹,Guo Rey-Ting¹,Cao Rong¹,No Joo Hwan¹,Liang Po-Huang¹,Ko Tzu-Ping¹,Chang Tao-Hsin¹,Chang Shiou-chi¹,Song Yongcheng¹,Axelson Jordan¹,Kumar Anup¹,Wang Andrew H.-J.¹,Oldfield Eric¹

Affiliation:

1. Institute of Biochemical Sciences, National Taiwan University, Taipei 106, Taiwan, Institute of Biological Chemistry, Academia Sinica, Taipei 115, Taiwan, Center for Biophysics and Computational Biology, University of Illinois at Urbana−Champaign, 607 South Mathews Avenue, Urbana, Illinois 61801, Core Facility for Protein Crystallography, Academia Sinica, Taipei 115, Taiwan, Department of Chemistry, University of Illinois at Urbana−Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800325y

Reference42 articles.

1. Human Geranylgeranyl Diphosphate Synthase

2. 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors Interfere With Angiogenesis by Inhibiting the Geranylgeranylation of RhoA

3. A Solanesyl-diphosphate Synthase Localizes in Glycosomes of Trypanosoma cruzi

4. Carotenoid biosynthesis: Isolation and characterization of a bifunctional enzyme catalyzing the synthesis of phytoene

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