Differences in the Cellular Uptake and Intracellular Itineraries of Amyloid Beta Proteins 40 and 42: Ramifications for the Alzheimer’s Drug Discovery-Reference-Cited by-同舟云学术

Differences in the Cellular Uptake and Intracellular Itineraries of Amyloid Beta Proteins 40 and 42: Ramifications for the Alzheimer’s Drug Discovery

Published:2012-06-01 Issue:7 Volume:9 Page:1887-1897
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Omtri Rajesh S.¹²,Davidson Michael W.³,Arumugam Balasubramaniam²,Poduslo Joseph F.⁴,Kandimalla Karunya K.¹⁴

Affiliation:

1. Division of Basic Pharmaceutical Sciences, Florida A&M University College of Pharmacy and Pharmaceutical Sciences, Tallahassee, Florida, United States

2. NIMS Institute of Pharmacy, NIMS University, Shoba Nagar, Delhi Highway, Jaipur, Rajasthan, India

3. National High Magnetic Field Laboratory and Department of Biological Science, The Florida State University, 1800 East Paul Dirac Drive, Tallahassee, Florida, United States

4. Molecular Neurobiology Laboratory, Departments of Neurology, Neuroscience, and Biochemistry/Molecular Biology, Mayo Clinic College of Medicine, Rochester, Minnesota, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp200530q

Reference42 articles.

1. Transient intraneuronal Aβ rather than extracellular plaque pathology correlates with neuron loss in the frontal cortex of APP/PS1KI mice

2. Intracellular amyloid-β in Alzheimer's disease

3. A modified beta-amyloid hypothesis: intraneuronal accumulation of the beta-amyloid peptide - the first step of a fatal cascade

4. Intraneuronal Aβ42 Accumulation in Human Brain

5. Aβ Immunotherapy Leads to Clearance of Early, but Not Late, Hyperphosphorylated Tau Aggregates via the Proteasome

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