In situ Monitoring of a Heterogeneous Etherification Reaction Using Quantitative Raman Spectroscopy

Author:

Hart Richard J.1,Pedge Nicholas I.1,Steven Alan R.1,Sutcliffe Kevin1

Affiliation:

1. Pharmaceutical Development, AstraZeneca, Silk Road Business Park, Macclesfield, SK10 2NA, United Kingdom

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Physical and Theoretical Chemistry

Reference16 articles.

1. Guidance for Industry, PAT a Framework for Innovative Pharmaceutical Development, Manufacturing and Quality Assurance;U.S. Department of Health and Human Services, Food and Drug Administration:Rockville, MD, U.S.A., September 2004.

2. Online NMR and HPLC as a Reaction Monitoring Platform for Pharmaceutical Process Development

3. Mass spectrometric approaches for the investigation of dynamic processes in condensed phase

4. On-line reaction monitoring by extractive electrospray ionisation

5. Selectivity Control by Use of Near-IR for a Hydrogenation Process

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