ERβ Ligands. 3. Exploiting Two Binding Orientations of the 2-Phenylnaphthalene Scaffold To Achieve ERβ Selectivity-Reference-Cited by-同舟云学术

ERβ Ligands. 3. Exploiting Two Binding Orientations of the 2-Phenylnaphthalene Scaffold To Achieve ERβ Selectivity

Published:2005-05-24 Issue:12 Volume:48 Page:3953-3979
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Mewshaw Richard E.¹,Edsall, Richard J.¹,Yang Cuijian¹,Manas Eric S.¹,Xu Zhang B.¹,Henderson Ruth A.¹,Keith, James C.¹,Harris Heather A.¹

Affiliation:

1. Chemical and Screening Sciences and Women's Health Research Institute, Wyeth Research, 500 Arcola Road, Collegeville, Pennsylvania 19426, and Chemical and Screening Sciences and Cardiovascular and Metabolic Diseases, Wyeth Research, 200 Cambridge Park Dr., Cambridge Massachusetts 02140

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm058173s

Reference44 articles.

1. ERβ: Identification and characterization of a novel human estrogen receptor

2. Tissue Distribution and Quantitative Analysis of Estrogen Receptor-α (ERα) and Estrogen Receptor-β (ERβ) Messenger Ribonucleic Acid in the Wild-Type and ERα-Knockout Mouse

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